Dr. M. Prakash Hande

Department of Physiology, Yong Loo Lin School of Medicine and Tembusu College, National University of Singapore

Talk by Dr. M. Prakash Hande

[Day 1]
10.45AM-11.30 AM
Theme: Scientific Talk : Mechanism-based combination therapy in cancer: Telomerase and DNA repair inhibition

Personal Information

Prakash Hande is currently working as an Associate Professor at the Department of Physiology, Yong Loo Lin School of Medicine, NUS and a Fellow at Tembusu College. He received his PhD in Radiation Biology and a Masters in Public Health in Occupational and Environmental Health. Dr Hande has worked at the following institutions before joining NUS as a faculty member in 2002: Department of Radiobiology, Kasturba Medical College, Manipal, India; Osaka University Medical School, Japan; Leiden University Medical Centre, Leiden, The Netherlands; Terry Fox Laboratory, British Columbia Cancer Research Centre, Vancouver, Canada; and Columbia University, New  York, USA.  He has published more than 150 peer-reviewed research articles with >11000 citations in international journals such as Nature Genetics, Cell, Science, Genes and Development and PNAS etc. (Scopus H-index: 52). His research interests are:  telomeres and telomerase in ageing and cancer, experimental cancer therapeutics and biomarkers of radiation exposure. Dr Hande is one of the pioneers who identified the role of DNA repair factors in telomere regulation in mammalian systems. Dr Hande teaches cancer biology and ageing for life sciences students and he teaches senior seminars such as Biomedicine and Singapore Society and Radiation and Society in  Tembusu College.  He holds adjunct professor appointments at the Vellore Institute of  Technology, Vellore, India and Mangalore University, Mangalore, India and a visiting faculty at KIIT University, Bhubaneswar, India. Dr. Hande is a visiting scientist at the  National Institute of Radiological Sciences, Chiba, Japan. He is the founding editor-in-chief of Genome Integrity, an online journal. He is an associate editor of  Frontiers in Genetics as well as the editorial board member of Mutation Research –  Genetic Toxicology and Environmental Mutagenesis. He was a consultant to the Division of Human Health, International Atomic Energy Agency, Vienna, Austria in 2015 -2016 during his sabbatical leave from NUS. Dr Hande is currently an expert member of the workgroup on “Biological mechanisms influencing health effects from low-dose radiation exposure” with the United Nations Scientific Committee on the Effects of Atomic  Radiation (UNSCEAR).  

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